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Proteomic analysis of chicken embryonic trachea and kidney tissues after infection in ovo by avian infectious bronchitis coronavirus.


ABSTRACT:

Background

Avian infectious bronchitis (IB) is one of the most serious diseases of economic importance in chickens; it is caused by the avian infectious coronavirus (IBV). Information remains limited about the comparative protein expression profiles of chicken embryonic tissues in response to IBV infection in ovo. In this study, we analyzed the changes of protein expression in trachea and kidney tissues from chicken embryos, following IBV infection in ovo, using two-dimensional gel electrophoresis (2-DE) coupled with matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry (MALDI-TOF-TOF MS).

Results

17 differentially expressed proteins from tracheal tissues and 19 differentially expressed proteins from kidney tissues were identified. These protein

SUBMITTER: Cao Z 

PROVIDER: S-EPMC3060854 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature