A fresh look at the Ramachandran plot and the occurrence of standard structures in proteins.

ABSTRACT: The Ramachandran plot is among the most central concepts in structural biology, seen in publications and textbooks alike. However, with the increasing numbers of known protein-structures and greater accuracy of ultra-high resolution protein structures, we are still learning more about the basic principles of protein structure. Here we use high fidelity conformational information to explore novel ways, such a geo-style and wrapped Ramachandran plots, to convey some of the basic aspects of the Ramachandran plot and of protein conformation. We point out the pressing need for a standard nomenclature for peptide conformation and propose such a nomenclature. Finally, we summarize some recent conceptual advances related to the building blocks of protein structure. The results for linear groups im

SUBMITTER: Hollingsworth SA 

PROVIDER: S-EPMC3061398 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature