Risk factors for corneal infiltrative events during continuous wear of silicone hydrogel contact lenses.

ABSTRACT:

Purpose

This study determined which microbiologic, clinical, demographic, and behavioral factors are associated with corneal infiltrative events (CIEs) during continuous wear of silicone hydrogel (SH) contact lenses.

Methods

Subjects (n = 205) were fitted with lotrafilcon A lenses for continuous wear and observed for 1 year. The main exposures of interest were corneal staining and bacterial lens contamination. Kaplan-Meier (KM) plots were used to estimate the cumulative unadjusted probability of remaining CIE free, and Cox proportional hazards regression was used to model the hazard of having a CIE, as a function of key predictor variables.

Results

The KM-unadjusted cumulative probability of remaining CIE free was 73.3%. Approximately 53% of subjects had repeated epis

SUBMITTER: Szczotka-Flynn L 

PROVIDER: S-EPMC3061493 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature