Gene expression throughout a vertebrate's embryogenesis.

ABSTRACT:

Background

Describing the patterns of gene expression during embryonic development has broadened our understanding of the processes and patterns that define morphogenesis. Yet gene expression patterns have not been described throughout vertebrate embryogenesis. This study presents statistical analyses of gene expression during all 40 developmental stages in the teleost Fundulus heteroclitus using four biological replicates per stage.

Results

Patterns of gene expression for 7,000 genes appear to be important as they recapitulate developmental timing. Among the 45% of genes with significant expression differences between pairs of temporally adjacent stages, significant differences in gene expression vary from as few as five to more than 660. Five adjacent stages have dispropor

SUBMITTER: Bozinovic G 

PROVIDER: S-EPMC3062618 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature