BTECH: a platform to integrate genomic, transcriptomic and epigenomic alterations in brain tumors.

ABSTRACT: The identification of molecular signatures predictive of clinical behavior and outcome in brain tumors has been the focus of many studies in the recent years. Despite the wealth of data that are available in the public domain on alterations in the genome, epigenome and transcriptome of brain tumors, the underlying molecular mechanisms leading to tumor initiation and progression remain largely unknown. Unfortunately, most of these data are scattered in multiple databases and supplementary materials of publications, thus making their retrieval, evaluation, comparison and visualization a rather arduous task. Here we report the development and implementation of an open access database (BTECH), a community resource for the deposition of a wide range of molecular data derived from brain tumor st

SUBMITTER: Wang M 

PROVIDER: S-EPMC3063551 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature