Effect of continuous glucose monitoring on hypoglycemia in type 1 diabetes.

ABSTRACT:

Objective

To assess the impact of continuous glucose monitoring on hypoglycemia in people with type 1 diabetes.

Research design and methods

In this randomized, controlled, multicenter study, 120 children and adults on intensive therapy for type 1 diabetes and a screening level of glycated hemoglobin A(1c) (HbA(1c)) <7.5% were randomly assigned to a control group performing conventional home monitoring with a blood glucose meter and wearing a masked continuous glucose monitor every second week for five days or to a group with real-time continuous glucose monitoring. The primary outcome was the time spent in hypoglycemia (interstitial glucose concentration <63 mg/dL) over a period of 26 weeks. Analysis was by intention to treat for all randomized patients.

Results

The t

SUBMITTER: Battelino T 

PROVIDER: S-EPMC3064030 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature