Metabolic syndrome and onset of depressive symptoms in the elderly: findings from the three-city study.

ABSTRACT:

Objective

Given the increasing prevalence of both metabolic syndrome (MetS) and depressive symptoms during old age, we aimed to examine prospectively the association between MetS and the onset of depressive symptoms according to different age-groups in a large, general elderly population.

Research design and methods

This was a prospective cohort study of 4,446 men and women aged 65-91 years who were free of depression or depressive symptoms at baseline (the Three-City Study, France). MetS was defined using the National Cholesterol Education Program Adult Treatment Panel III criteria. New onset of depressive symptoms (the Center for Epidemiologic Studies Depression Scale score ≥16 and use of antidepressant treatment) was assessed at 2- and 4-year follow-ups.

Results

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SUBMITTER: Akbaraly TN 

PROVIDER: S-EPMC3064049 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature