Base-mediated intermolecular sp2 C-H bond arylation via benzyne intermediates.

ABSTRACT: A transition-metal-free method for arylation of heterocycle and arene carbon-hydrogen bonds by aryl chlorides and fluorides has been developed. The reactions proceed via aryne intermediates and are highly regioselective with respect to the C-H bond coupling component.

SUBMITTER: Truong T 

PROVIDER: S-EPMC3065930 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature