Inhibition of Streptococcus mutans biofilm formation by Streptococcus salivarius FruA.

ABSTRACT: The oral microbial flora consists of many beneficial species of bacteria that are associated with a healthy condition and control the progression of oral disease. Cooperative interactions between oral streptococci and the pathogens play important roles in the development of dental biofilms in the oral cavity. To determine the roles of oral streptococci in multispecies biofilm development and the effects of the streptococci in biofilm formation, the active substances inhibiting Streptococcus mutans biofilm formation were purified from Streptococcus salivarius ATCC 9759 and HT9R culture supernatants using ion exchange and gel filtration chromatography. Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry analysis was performed, and the results were compare

SUBMITTER: Ogawa A 

PROVIDER: S-EPMC3067281 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature