Assessing autonomic dysfunction in early diabetic neuropathy: the Survey of Autonomic Symptoms.

ABSTRACT:

Objective

Autonomic symptoms may occur frequently in diabetic and other neuropathies. There is a need to develop a simple instrument to measure autonomic symptoms in subjects with neuropathy and to test the validity of the instrument.

Methods

The Survey of Autonomic Symptoms (SAS) consists of 11 items in women and 12 in men. Each item is rated by an impact score ranging from 1 (least severe) to 5 (most severe). The SAS was tested in observational studies and compared to a previously validated autonomic scale, the Autonomic Symptom Profile (ASP), and to a series of autonomic tests.

Results

The SAS was tested in 30 healthy controls and 62 subjects with neuropathy and impaired glucose tolerance or newly diagnosed diabetes. An increased SAS score was associated with the p

SUBMITTER: Zilliox L 

PROVIDER: S-EPMC3068012 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature