Determining the enantioselectivity of chiral catalysts by mass spectrometric screening of their racemic forms.

ABSTRACT: The enantioselectivity of a chiral catalyst can be determined from its racemic form by mass spectrometric screening of a nonequal mixture of two mass-labeled quasienantiomeric substrates. The presented method opens up new possibilities for evaluating catalyst structures that are not readily available in enantiomerically pure form.

SUBMITTER: Ebner C 

PROVIDER: S-EPMC3068606 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature