Partial volume correction incorporating Rb-82 positron range for quantitative myocardial perfusion PET based on systolic-diastolic activity ratios and phantom measurements.

ABSTRACT:

Background

Quantitative myocardial PET perfusion imaging requires partial volume corrections.

Methods

Patients underwent ECG-gated, rest-dipyridamole, myocardial perfusion PET using Rb-82 decay corrected in Bq/cc for diastolic, systolic, and combined whole cycle ungated images. Diastolic partial volume correction relative to systole was determined from the systolic/diastolic activity ratio, systolic partial volume correction from phantom dimensions comparable to systolic LV wall thicknesses and whole heart cycle partial volume correction for ungated images from fractional systolic-diastolic duration for systolic and diastolic partial volume corrections.

Results

For 264 PET perfusion images from 159 patients (105 rest-stress image pairs, 54 individual rest or stress im

SUBMITTER: Johnson NP 

PROVIDER: S-EPMC3069317 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature