Proteome and transcriptome profiles of a Her2/Neu-driven mouse model of breast cancer.

ABSTRACT:

Purpose

We generated extensive transcriptional and proteomic profiles from a Her2-driven mouse model of breast cancer that closely recapitulates human breast cancer. This report makes these data publicly available in raw and processed forms, as a resource to the community. Importantly, we previously made biospecimens from this same mouse model freely available through a sample repository, so researchers can obtain samples to test biological hypotheses without the need of breeding animals and collecting biospecimens.

Experimental design

Twelve datasets are available, encompassing 841 LC-MS/MS experiments (plasma and tissues) and 255 microarray analyses of multiple tissues (thymus, spleen, liver, blood cells, and breast). Cases and controls were rigorously paired to avoid bias

SUBMITTER: Schoenherr RM 

PROVIDER: S-EPMC3069718 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature