Early weaning increases diarrhea morbidity and mortality among uninfected children born to HIV-infected mothers in Zambia.

ABSTRACT:

Background

Early weaning may reduce human immunodeficiency virus (HIV) transmission but may have deleterious consequences for uninfected children. Here we evaluate effects of early weaning on diarrhea morbidity and mortality of uninfected children born to HIV-infected mothers.

Methods

HIV-infected women in Lusaka, Zambia, were randomly assigned to breastfeeding for 4 months only or to continue breastfeeding until the mother decided to stop. Replacement and complementary foods were provided and all women were counseled around feeding and hygiene. Diarrhea morbidity and mortality were assessed in 618 HIV-uninfected singletons alive and still breastfeeding at 4 months. Intent-to-treat analyses and comparisons based on actual feeding practices were conducted using regression met

SUBMITTER: Fawzy A 

PROVIDER: S-EPMC3069726 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature