Lisdexamfetamine dimesylate for the treatment of attention deficit hyperactivity disorder in adults with a history of depression or history of substance use disorder.

ABSTRACT:

Objective

To evaluate the efficacy and safety of lisdexamfetamine dimesylate in participants with attention deficit hyperactivity disorder and a history of depression and/or substance use disorder. History of these comorbidities was recorded from medical history forms completed by the study clinicians.

Design/setting

An exploratory, post-hoc analysis was conducted using data from a randomized, double-blind, placebo-controlled, forced-dose titration study of lisdexamfetamine dimesylate.

Participants

Adults with attention deficit hyperactivity disorder.

Measurements

Changes in Attention Deficit Hyperactivity Disorder Rating Scale IV total scores and Clinical Global Impressions-Improvement scale were used to evaluate the efficacy of lisdexamfetamine dimesylate. Th

SUBMITTER: Kollins SH 

PROVIDER: S-EPMC3071091 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature