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Industry involvement and baseline assumptions of cost-effectiveness analyses: diagnostic accuracy of the Papanicolaou test.


ABSTRACT:

Background

Industry involvement has been associated with more favourable cost-effectiveness ratios in cost-effectiveness analyses, but the mechanisms for this association are unclear. We evaluated whether the assumed accuracy of the Papanicolaou (Pap) test was correlated with the features of cost-effectiveness analysis studies.

Methods

We searched PubMed (last updated April 2010) for cost-effectiveness analysis studies in which at least one strategy involved the Pap test for cervical cancer. We assessed the baseline assumed diagnostic sensitivity and specificity of the Pap test in each study and the association of these values with three levels of manufacturer involvement in the study.

Results

Among 88 analyzed cost-effectiveness analysis studies, the assumed sensitiv

SUBMITTER: Polyzos NP 

PROVIDER: S-EPMC3071415 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature