Steroids and bronchodilators for acute bronchiolitis in the first two years of life: systematic review and meta-analysis.

ABSTRACT:

Objective

To evaluate and compare the efficacy and safety of bronchodilators and steroids, alone or combined, for the acute management of bronchiolitis in children aged less than 2 years.

Design

Systematic review and meta-analysis.

Data sources

Medline, Embase, Central, Scopus, PubMed, LILACS, IranMedEx, conference proceedings, and trial registers. Inclusion criteria Randomised controlled trials of children aged 24 months or less with a first episode of bronchiolitis with wheezing comparing any bronchodilator or steroid, alone or combined, with placebo or another intervention (other bronchodilator, other steroid, standard care).

Review methods

Two reviewers assessed studies for inclusion and risk of bias and extracted data. Primary outcomes were selected by cli

SUBMITTER: Hartling L 

PROVIDER: S-EPMC3071611 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature