Controlling instabilities in manipulation requires specific cortical-striatal-cerebellar networks.

ABSTRACT: Dexterous manipulation requires both strength, the ability to produce fingertip forces of a specific magnitude, and dexterity, the ability to dynamically regulate the magnitude and direction of fingertip force vectors and finger motions. Although cortical activity in fronto-parietal networks has been established for stable grip and pinch forces, the cortical regulation in the dexterous control of unstable objects remains unknown. We used functional magnetic resonance imaging (fMRI) to interrogate cortical networks engaged in the control of four objects with increasing instabilities but requiring constant strength. In addition to expected activity in fronto-parietal networks we find that dexterous manipulation of increasingly unstable objects is associated with a linear increase in the ampl

SUBMITTER: Mosier K 

PROVIDER: S-EPMC3074419 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature