Lung volumes and emphysema in smokers with interstitial lung abnormalities.

ABSTRACT:

Background

Cigarette smoking is associated with emphysema and radiographic interstitial lung abnormalities. The degree to which interstitial lung abnormalities are associated with reduced total lung capacity and the extent of emphysema is not known.

Methods

We looked for interstitial lung abnormalities in 2416 (96%) of 2508 high-resolution computed tomographic (HRCT) scans of the lung obtained from a cohort of smokers. We used linear and logistic regression to evaluate the associations between interstitial lung abnormalities and HRCT measurements of total lung capacity and emphysema.

Results

Interstitial lung abnormalities were present in 194 (8%) of the 2416 HRCT scans evaluated. In statistical models adjusting for relevant covariates, interstitial lung abnormalities

SUBMITTER: Washko GR 

PROVIDER: S-EPMC3074462 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature