Association between body mass index and arsenic methylation efficiency in adult women from southwest U.S. and northwest Mexico.

ABSTRACT: Human arsenic methylation efficiency has been consistently associated with arsenic-induced disease risk. Interindividual variation in arsenic methylation profiles is commonly observed in exposed populations, and great effort has been put into the study of potential determinants of this variability. Among the factors that have been evaluated, body mass index (BMI) has not been consistently associated with arsenic methylation efficiency; however, an underrepresentation of the upper BMI distribution was commonly observed in these studies. This study investigated potential factors contributing to variations in the metabolism of arsenic, with specific interest in the effect of BMI where more than half of the population was overweight or obese. We studied 624 adult women exposed to arsenic in dr

SUBMITTER: Gomez-Rubio P 

PROVIDER: S-EPMC3075343 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature