Relationship between cingulo-insular functional connectivity and autistic traits in neurotypical adults.

ABSTRACT:

Objective

The Social Responsiveness Scale-Adult Version (SRS-A) measures autistic traits that are continuously distributed in the general population. Based on increased recognition of the dimensional nature of autistic traits, the authors examined the neural correlates of these traits in neurotypical individuals using the SRS-A and established a novel approach to assessing the neural basis of autistic characteristics, attempting to directly relate SRS-A scores to patterns of functional connectivity observed in the pregenual anterior cingulate cortex, a region commonly implicated in social cognition.

Method

Resting state functional magnetic resonance imaging scans were collected for 25 neurotypical adults. All participants provided SRS-A ratings completed by an informant who

SUBMITTER: Di Martino A 

PROVIDER: S-EPMC3075727 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature