Neuroimaging in multiple sclerosis: neurotherapeutic implications.

ABSTRACT: Imaging techniques, in particular magnetic resonance imaging (MRI), play an important role in the diagnosis and management of multiple sclerosis (MS) and related demyelinating diseases. Findings on MRI studies of the brain and spinal cord are critical for MS diagnosis, are used to monitor treatment response and may aid in predicting disease progression in individual patients. In addition, results of imaging studies serve as essential biomarkers in clinical trials of putative MS therapies and have led to important insights into disease pathophysiology. Although they are useful tools and provide in vivo measures of disease-related activity, there are some important limitations of MRI findings in MS, including the non-specific nature of detectable white matter changes, the poor correlation wi

SUBMITTER: Sicotte NL 

PROVIDER: S-EPMC3075734 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature