Proteomic analysis of the marine diatom Thalassiosira pseudonana upon exposure to benzo(a)pyrene.

ABSTRACT:

Background

Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants ubiquitously distributed. They are generated by incomplete combustion of organic materials such as wood or fossil fuels. Due to their carcinogenic, mutagenic effects and to their wide distribution in the environment, these pollutants pose many concerns to researchers and regulators. In our laboratories we investigated the effect of benzo(a)pyrene (BaP) exposure in the marine diatom Thalassiosira pseudonana, which has become an important model organism in aquatic toxicology studies.

Results

In order to investigate the mechanism of action of PAHs, we exposed the diatoms for 24 h to 36.45 μg/L of BaP which inhibits the growth by about 30%, and analysed the relative protein expression profile by a qu

SUBMITTER: Carvalho RN 

PROVIDER: S-EPMC3076255 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature