Assessing the influence of different ROI selection strategies on functional connectivity analyses of fMRI data acquired during steady-state conditions.

ABSTRACT: In blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI), assessing functional connectivity between and within brain networks from datasets acquired during steady-state conditions has become increasingly common. However, in contrast to connectivity analyses based on task-evoked signal changes, selecting the optimal spatial location of the regions of interest (ROIs) whose timecourses will be extracted and used in subsequent analyses is not straightforward. Moreover, it is also unknown how different choices of the precise anatomical locations within given brain regions influence the estimates of functional connectivity under steady-state conditions. The objective of the present study was to assess the variability in estimates of functional connectivity induced by d

SUBMITTER: Marrelec G 

PROVIDER: S-EPMC3076321 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature