End-functionalized ROMP polymers for Biomedical Applications.

ABSTRACT: We present two novel allyl-based terminating agents that can be used to end-functionalize living polymer chains obtained by ring-opening metathesis polymerization (ROMP) using Grubbs' third generation catalyst. Both terminating agents can be easily synthesized and yield ROMP polymers with stable, storable activated ester groups at the chain-end. These end-functionalized ROMP polymers are attractive building blocks for advanced polymeric materials, especially in the biomedical field. Dye-labeling and surface-coupling of antimicrobially active polymers using these end-groups were demonstrated.

SUBMITTER: Madkour AE 

PROVIDER: S-EPMC3076928 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature