Magnetic resonance velocity imaging derived pressure differential using control volume analysis.

ABSTRACT:

Background

Diagnosis and treatment of hydrocephalus is hindered by a lack of systemic understanding of the interrelationships between pressures and flow of cerebrospinal fluid in the brain. Control volume analysis provides a fluid physics approach to quantify and relate pressure and flow information. The objective of this study was to use control volume analysis and magnetic resonance velocity imaging to non-invasively estimate pressure differentials in vitro.

Method

A flow phantom was constructed and water was the experimental fluid. The phantom was connected to a high-resolution differential pressure sensor and a computer controlled pump producing sinusoidal flow. Magnetic resonance velocity measurements were taken and subsequently analyzed to derive pressure differential

SUBMITTER: Cohen B 

PROVIDER: S-EPMC3077315 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature