Quantifying the link between anatomical connectivity, gray matter volume and regional cerebral blood flow: an integrative MRI study.

ABSTRACT:

Background

In the graph theoretical analysis of anatomical brain connectivity, the white matter connections between regions of the brain are identified and serve as basis for the assessment of regional connectivity profiles, for example, to locate the hubs of the brain. But regions of the brain can be characterised further with respect to their gray matter volume or resting state perfusion. Local anatomical connectivity, gray matter volume and perfusion are traits of each brain region that are likely to be interdependent, however, particular patterns of systematic covariation have not yet been identified.

Methodology/principal findings

We quantified the covariation of these traits by conducting an integrative MRI study on 23 subjects, utilising a combination of Diffusion Ten

SUBMITTER: Varkuti B 

PROVIDER: S-EPMC3078126 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature