Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis.

ABSTRACT:

Objective

To perform a review and metaanalysis of the studies evaluating the status of serum inflammatory markers in women with polycystic ovary syndrome (PCOS).

Design

Systematic review and metaanalysis of articles published in English before January 2010 and identified using the PubMed search engine.

Setting

Academic hospital.

Patient(s)

Women with PCOS and appropriate controls.

Intervention(s)

Measurement of serum concentrations of inflammatory markers by high-sensitivity techniques.

Main outcome measure(s)

Metaanalyses of the mean difference in serum C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) concentrations among patients with PCOS and appropriate controls, applying random-effects models to limit interst

SUBMITTER: Escobar-Morreale HF 

PROVIDER: S-EPMC3079565 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature