Haemodynamic consequences of changing potassium concentrations in haemodialysis fluids.

ABSTRACT:

Background

A rapid decrease of serum potassium concentrations during haemodialysis produces a significant increase in blood pressure parameters at the end of the session, even if effects on intra-dialysis pressure are not seen. Paradoxically, in animal models potassium is a vasodilator and decreases myocardial contractility. The purpose of this trial is to study the precise haemodynamic consequences induced by acute changes in potassium concentration during haemodialysis.

Methods

In 24 patients, 288 dialysis sessions, using a randomised single blind crossover design, we compared six dialysate sequences with different potassium profiles. The dialysis sessions were divided into 3 tertiles, casually modulating potassium concentration in the dialysate between the value normally

SUBMITTER: Gabutti L 

PROVIDER: S-EPMC3079606 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature