Upper airway structure and body fat composition in obese children with obstructive sleep apnea syndrome.

ABSTRACT:

Rationale

Mechanisms leading to obstructive sleep apnea syndrome (OSAS) in obese children are not well understood.

Objectives

The aim of the study was to determine anatomical risk factors associated with OSAS in obese children as compared with obese control subjects without OSAS.

Methods

Magnetic resonance imaging was used to determine the size of upper airway structure, and body fat composition. Paired analysis was used to compare between groups. Mixed effects regression models and conditional multiple logistic regression models were used to determine whether body mass index (BMI) Z-score was an effect modifier of each anatomic characteristic as it relates to OSAS.

Measurements and main results

We studied 22 obese subjects with OSAS (12.5 ± 2.8 yr; BMI Z-score

SUBMITTER: Arens R 

PROVIDER: S-EPMC3081285 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature