Increased mortality risk in women with depression and diabetes mellitus.

ABSTRACT:

Context

Depression and diabetes mellitus have been associated with an increased risk of all-cause and cardiovascular disease (CVD) mortality. However, data evaluating the joint effects of these 2 conditions on mortality are sparse.

Objectives

To evaluate the individual and joint effects of depression and diabetes on all-cause and CVD mortality rate.

Design

Prospective cohort study.

Setting

The 11 states of the Nurses' Health Study.

Participants

A total of 78 282 women who participated in the Nurses' Health Study aged 54 to 79 years at baseline in 2000 were followed up until 2006. Depression was defined as having self-reported diagnosed depression, treatment with antidepressant medications, or a score indicating severe depressive symptoms (ie, a 5-item Me

SUBMITTER: Pan A 

PROVIDER: S-EPMC3081788 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature