Pre-admission statin use and in-hospital severity of 2009 pandemic influenza A(H1N1) disease.

ABSTRACT:

Background

Statins are drugs that are used to lower plasma cholesterol levels. Recently, contradictory claims have been made about possible additional effects of statins on progression of a variety of inflammatory disorders, including infections. We therefore examined the clinical course of patients admitted to hospital with 2009 pandemic influenza A(H1N1), who were or weren't taking statins at time of admission.

Methods

A retrospective case-control study was performed using the United Kingdom Influenza Clinical Information Network (FLU-CIN) database, containing detailed information on 1,520 patients admitted to participating hospitals with confirmed 2009 pandemic influenza A(H1N1) infection between April 2009 and January 2010. We confined our analysis to those aged over 34

SUBMITTER: Brett SJ 

PROVIDER: S-EPMC3081811 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature