Effects of diet and physical activity interventions on weight loss and cardiometabolic risk factors in severely obese adults: a randomized trial.

ABSTRACT:

Context

The prevalence of severe obesity is increasing markedly, as is prevalence of comorbid conditions such as hypertension and type 2 diabetes mellitus; however, apart from bariatric surgery and pharmacotherapy, few clinical trials have evaluated the treatment of severe obesity.

Objective

To determine the efficacy of a weight loss and physical activity intervention on the adverse health risks of severe obesity.

Design, setting, and participants

Single-blind randomized trial conducted from February 2007 through April 2010 at the University of Pittsburgh. Participants were 130 (37% African American) severely obese (class II or III) adult participants without diabetes recruited from the community.

Interventions

One-year intensive lifestyle intervention consisti

SUBMITTER: Goodpaster BH 

PROVIDER: S-EPMC3082279 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature