Rh2(II)-catalyzed nitro-group migration reactions: selective synthesis of 3-nitroindoles from β-nitro styryl azides.

ABSTRACT: Rhodium carboxylate complexes (1 mol %) catalyze the migration of electron-withdrawing groups to selectively produce 3-substituted indoles from β-substituted styryl azides. The relative order of migratorial aptitude for this transformation is ester ≪ amide < H < sulfonyl < benzoyl ≪ nitro.

SUBMITTER: Stokes BJ 

PROVIDER: S-EPMC3082431 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature