Gene Atlasing of digestive and reproductive tissues in Schistosoma mansoni.

ABSTRACT:

Background

While considerable genomic and transcriptomic data are available for Schistosoma mansoni, many of its genes lack significant annotation. A transcriptomic study of individual tissues and organs of schistosomes could play an important role in functional annotation of the unknown genes, particularly by providing rapid localisation data and thus giving insight into the potential roles of these molecules in parasite development, reproduction and homeostasis, and in the complex host-parasite interaction.

Methodology/principal findings

Quantification of gene expression in tissues of S. mansoni was achieved by a combination of laser microdissection microscopy (LMM) and oligonucleotide microarray analysis. We compared the gene expression profile of the adult female gastrod

SUBMITTER: Nawaratna SS 

PROVIDER: S-EPMC3082511 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature