Genealogical lineage sorting leads to significant, but incorrect Bayesian multilocus inference of population structure.

ABSTRACT: Over the past decades, the use of molecular markers has revolutionized biology and led to the foundation of a new research discipline-phylogeography. Of particular interest has been the inference of population structure and biogeography. While initial studies focused on mtDNA as a molecular marker, it has become apparent that selection and genealogical lineage sorting could lead to erroneous inferences. As it is not clear to what extent these forces affect a given marker, it has become common practice to use the combined evidence from a set of molecular markers as an attempt to recover the signals that approximate the true underlying demography. Typically, the number of markers used is determined by either budget constraints or by statistical power required to recognize significant populat

SUBMITTER: Orozco-terWengel P 

PROVIDER: S-EPMC3084510 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature