Frontotemporal brain sagging syndrome: an SIH-like presentation mimicking FTD.

ABSTRACT:

Background

Behavioral variant frontotemporal dementia (bvFTD) is a relatively well-defined clinical syndrome. It is associated with frontal and temporal lobe structural/metabolic changes and pathologic findings of a neurodegenerative disease. We have been evaluating patients with clinical and imaging features partially consistent with bvFTD but with evidence also suggestive of brain sagging, which we refer to as frontotemporal brain sagging syndrome (FBSS).

Methods

Retrospective medical chart review to identify all patients seen at our institution between 1996 and 2010, who had a clinical diagnosis of FTD and imaging evidence of brain sag.

Results

Eight patients, 7 male and 1 female, were diagnosed with FBSS. The median age at symptom onset was 53 years. All patients

SUBMITTER: Wicklund MR 

PROVIDER: S-EPMC3087405 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature