Polymorphisms in bovine immune genes and their associations with somatic cell count and milk production in dairy cattle.

ABSTRACT:

Background

Mastitis, an inflammation of the mammary gland, is a major source of economic loss on dairy farms. The aim of this study was to quantify the associations between two previously identified polymorphisms in the bovine toll-like receptor 2 (TLR2) and chemokine receptor 1 (CXCR1) genes and mammary health indictor traits in (a) 246 lactating dairy cow contemporaries representing five breeds from one research farm and (b) 848 Holstein-Friesian bulls that represent a large proportion of the Irish dairy germplasm. To expand the study, a further 14 polymorphisms in immune genes were included for association studies in the bull population.

Results

TLR4-2021 associated (P < 0.05) with both milk protein and fat percentage in late lactation (P < 0.01) within the cow cohort. No

SUBMITTER: Beecher C 

PROVIDER: S-EPMC3087511 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature