The tmRNA website: reductive evolution of tmRNA in plastids and other endosymbionts.

ABSTRACT: tmRNA combines tRNA- and mRNA-like properties and ameliorates problems arising from stalled ribosomes. Research on the mechanism, structure and biology of tmRNA is served by the tmRNA website (http://www.indiana.edu/~ tmrna), a collection of sequences, alignments, secondary structures and other information. Because many of these sequences are not in GenBank, a BLAST server has been added; another new feature is an abbreviated alignment for the tRNA-like domain only. Many tmRNA sequences from plastids have been added, five found in public sequence data and another 10 generated by direct sequencing; detection in early-branching members of the green plastid lineage brings coverage to all three primary plastid lineages. The new sequences include the shortest known tmRNA sequence. While bacteri

SUBMITTER: Gueneau de Novoa P 

PROVIDER: S-EPMC308836 | biostudies-literature | 2004 Jan

REPOSITORIES: biostudies-literature