A high-resolution linkage map for comparative genome analysis and QTL fine mapping in Asian seabass, Lates calcarifer.

ABSTRACT:

Background

High density linkage maps are essential for comparative analysis of synteny, fine mapping of quantitative trait loci (QTL), searching for candidate genes and facilitating genome sequence assembly. However, in most foodfish species, marker density is still low. We previously reported a first generation linkage map with 240 DNA markers and its application to preliminarily map QTL for growth traits in Asian seabass (Lates calcarifer). Here, we report a high-resolution linkage map with 790 microsatellites and SNPs, comparative analysis of synteny, fine-mapping of QTL and the identification of potential candidate genes for growth traits.

Results

A second generation linkage map of Asian seabass was developed with 790 microsatellite and SNP markers. The map spanned a gen

SUBMITTER: Wang CM 

PROVIDER: S-EPMC3088568 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature