Association of the presence of Helicobacter in gallbladder tissue with cholelithiasis and cholecystitis.

ABSTRACT: The presence of Helicobacter DNA species has been investigated in the biliary epithelium of patients with biliary diseases. However, conflicting results have been observed that may have been due to the small number of subjects studied, difficulty in obtaining a healthy control group, absence of controlling for confounding factors, or differences among populations. Therefore, we investigated the presence of Helicobacter species by culture and nested PCR of 16S rRNA genes in gallbladder tissue and bile from 46 Brazilian subjects with and 18 without cholelithiasis. The control group was mainly composed of liver donors and of patients who had submitted to cholecystectomy as part of the surgical treatment for morbid obesity. No Helicobacter species were grown from the bile or gallbladder tissue

SUBMITTER: Silva CP 

PROVIDER: S-EPMC309000 | biostudies-literature | 2003 Dec

REPOSITORIES: biostudies-literature