A novel tissue-specific meta-analysis approach for gene expression predictions, initiated with a mammalian gene expression testis database.

ABSTRACT:

Background

In the recent years, there has been a rise in gene expression profiling reports. Unfortunately, it has not been possible to make maximum use of available gene expression data. Many databases and programs can be used to derive the possible expression patterns of mammalian genes, based on existing data. However, these available resources have limitations. For example, it is not possible to obtain a list of genes that are expressed in certain conditions. To overcome such limitations, we have taken up a new strategy to predict gene expression patterns using available information, for one tissue at a time.

Results

The first step of this approach involved manual collection of maximum data derived from large-scale (genome-wide) gene expression studies, pertaining to mamm

SUBMITTER: Acharya KK 

PROVIDER: S-EPMC3091663 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature