Genome analysis and comparative genomics of a Giardia intestinalis assemblage E isolate.

ABSTRACT:

Background

Giardia intestinalis is a protozoan parasite that causes diarrhea in a wide range of mammalian species. To further understand the genetic diversity between the Giardia intestinalis species, we have performed genome sequencing and analysis of a wild-type Giardia intestinalis sample from the assemblage E group, isolated from a pig.

Results

We identified 5012 protein coding genes, the majority of which are conserved compared to the previously sequenced genomes of the WB and GS strains in terms of microsynteny and sequence identity. Despite this, there is an unexpectedly large number of chromosomal rearrangements and several smaller structural changes that are present in all chromosomes. Novel members of the VSP, NEK Kinase and HCMP gene families were identified, whic

SUBMITTER: Jerlstrom-Hultqvist J 

PROVIDER: S-EPMC3091692 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature