Gene duplications in prokaryotes can be associated with environmental adaptation.

ABSTRACT:

Background

Gene duplication is a normal evolutionary process. If there is no selective advantage in keeping the duplicated gene, it is usually reduced to a pseudogene and disappears from the genome. However, some paralogs are retained. These gene products are likely to be beneficial to the organism, e.g. in adaptation to new environmental conditions. The aim of our analysis is to investigate the properties of paralog-forming genes in prokaryotes, and to analyse the role of these retained paralogs by relating gene properties to life style of the corresponding prokaryotes.

Results

Paralogs were identified in a number of prokaryotes, and these paralogs were compared to singletons of persistent orthologs based on functional classification. This showed that the paralogs were asso

SUBMITTER: Bratlie MS 

PROVIDER: S-EPMC3091735 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature