Parental smoking during pregnancy and offspring bone mass at age 10 years: findings from a prospective birth cohort.

ABSTRACT:

Unlabelled

We investigated an intrauterine influence of maternal smoking during pregnancy on childhood bone mass. Daughters, but not sons, of mothers who smoked had higher bone mass at age 10years. This appears to be due to familial factors related to parental smoking influencing increased offspring adiposity rather than a direct intrauterine effect.

Introduction

Neonatal studies have demonstrated an adverse relationship between maternal smoking in pregnancy and foetal bone mineral accrual. We aimed to investigate an intrauterine influence of maternal smoking during pregnancy on offspring bone mass at mean age 9.9 years.

Methods

We compared associations of maternal and paternal smoking in pregnancy with offspring total body less head (TBLH) and spine bone mineral cont

SUBMITTER: Macdonald-Wallis C 

PROVIDER: S-EPMC3092913 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature