Expression variability of co-regulated genes differentiates Saccharomyces cerevisiae strains.

ABSTRACT:

Background

Saccharomyces cerevisiae (Baker's yeast) is found in diverse ecological niches and is characterized by high adaptive potential under challenging environments. In spite of recent advances on the study of yeast genome diversity, little is known about the underlying gene expression plasticity. In order to shed new light onto this biological question, we have compared transcriptome profiles of five environmental isolates, clinical and laboratorial strains at different time points of fermentation in synthetic must medium, during exponential and stationary growth phases.

Results

Our data unveiled diversity in both intensity and timing of gene expression. Genes involved in glucose metabolism and in the stress response elicited during fermentation were among the most vari

SUBMITTER: Carreto L 

PROVIDER: S-EPMC3094312 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature