Stereoselective synthesis of a model C(18)-C(35) spiroketal fragment of integramycin.

ABSTRACT: A highly stereoselective synthesis of a model C(18)-C(35) spiroketal unit (7) of integramycin has been accomplished via an enantioselective stannyl-crotylboration reaction and an N-iodosuccinimide-mediated spiroketalization of 19a.

SUBMITTER: Sun H 

PROVIDER: S-EPMC3094501 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature