Unexpected complexity of the reef-building coral Acropora millepora transcription factor network.

ABSTRACT:

Background

Coral reefs are disturbed on a global scale by environmental changes including rising sea surface temperatures and ocean acidification. Little is known about how corals respond or adapt to these environmental changes especially at the molecular level. This is mostly because of the paucity of genome-wide studies on corals and the application of systems approaches that incorporate the latter. Like in any other organism, the response of corals to stress is tightly controlled by the coordinated interplay of many transcription factors.

Results

Here, we develop and apply a new system-wide approach in order to infer combinatorial transcription factor networks of the reef-building coral Acropora millepora. By integrating sequencing-derived transcriptome measurements, a ne

SUBMITTER: Ryu T 

PROVIDER: S-EPMC3096595 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature