Frontal-to-parietal top-down causal streams along the dorsal attention network exclusively mediate voluntary orienting of attention.

ABSTRACT: Previous effective connectivity analyses of functional magnetic resonance imaging (fMRI) have revealed dynamic causal streams along the dorsal attention network (DAN) during voluntary attentional control in the human brain. During resting state, however, fMRI has shown that the DAN is also intrinsically configured by functional connectivity, even in the absence of explicit task demands, and that may conflict with effective connectivity studies. To resolve this contradiction, we performed an effective connectivity analysis based on partial Granger causality (pGC) on event-related fMRI data during Posner's cueing paradigm while optimizing experimental and imaging parameters for pGC analysis. Analysis by pGC can factor out exogenous or latent influences due to unmeasured variables. Typical re

SUBMITTER: Ozaki TJ 

PROVIDER: S-EPMC3096666 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature