National Cancer Institute Prostate Cancer Genetics Workshop.

ABSTRACT: Compelling evidence supports a genetic component to prostate cancer susceptibility and aggressiveness. Recent genome-wide association studies have identified more than 30 single-nucleotide polymorphisms associated with prostate cancer susceptibility. It remains unclear, however, whether such genetic variants are associated with disease aggressiveness--one of the most important questions in prostate cancer research today. To help clarify this and substantially expand research in the genetic determinants of prostate cancer aggressiveness, the first National Cancer Institute Prostate Cancer Genetics Workshop assembled researchers to develop plans for a large new research consortium and patient cohort. The workshop reviewed the prior work in this area and addressed the practical issues in plan

SUBMITTER: Catalona WJ 

PROVIDER: S-EPMC3096727 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature